Keywords
Anos de Vida Perdidos
Região Norte
Disparidades em Saúde
Perimenopausa
How to Cite
Abstract
This retrospective study assessed the Years of Potential Life Lost (YPLL) and the Adjusted Rate per 1,000 Women (ARYPLL) due to endometrial cancer and uterus not otherwise specified (NOS) in Northern Brazil from 2012 to 2022, using data from the Cancer Mortality Atlas of the Ministry of Health. The total ARYPLL ranged from 0.14 (Acre) to 0.35 (Amapá) per 1,000 women, with Pará recording the highest absolute YPLL (12,815 years). The 50-59 age group showed the highest ARYPLL peaks, particularly in Roraima (1.47) and Amapá (1.17), while the 40-49 age group was also significant (maximum ARYPLL of 1.12 in Amapá). No significant losses were observed below 15 years. The concentration of YPLL between 40-59 years suggests an association with perimenopausal factors and metabolic risks, exacerbated by regional disparities, such as limited healthcare infrastructure in Pará and Amazonas. Global comparisons reveal similarities with aging population patterns in Shanghai and high mortality rates in low-income countries. The findings underscore the need for public health policies focused on prevention, screening, and equitable treatment access to reduce the burden of gynecological cancers in the region.
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